Funny but serious questions about HUGE cats and MINIATURE cats!?

Okay so call me odd but I seem to have developed a love for very huge cats (Maine Coon specifically) and miniature or dwarf cats. One day when I’m financially stable (have a house) I’d like to have one of each (Maine Coon and dwarf/miniature cat) as house pets, but I’m scared that the big cat will eat the little cat lol. Okay maybe not eat, but possibly do serious bodily harm whether intentional or unintentional. See, I have this cat named Midnight that I found and raised as a stray and she hates when other cats are in our home. She does this scary threatening hissing growl thing as a warning to that cat, so that’s why I’m concerned. If a huge cat feels threatened by a dwarf or miniature cat, than the huge cat in my opinion can easily solve that problem. Another scenario, Maine Coon cats are so loving and playful and what if she wants to play with the little cat? It wouldn’t take much for such a huge cat to harm such a small cat. Any advice or suggestions would be greatly appreciated!